鍗靛艦椴抽補(bǔ)瑙勬ā鍖栫箒鑲插拰鍋ュ悍楂樻晥鍏繪畺鎶�鏈爺絀朵笌浜т笟鍖栧簲鐢?/h3>
欏圭洰鍚嶇О錛氬嵉褰㈤渤椴硅妯″寲綣佽偛鍜屽仴搴烽珮鏁堝吇孌栨妧鏈爺絀朵笌浜т笟鍖栧簲鐢?/p>
鑾峰鍚嶇О鍙?qiáng)绛壘Uэ細(xì)2019騫村害嫻峰崡鐪佺瀛︽妧鏈浜岀瓑濂?/p>
涓昏瀹屾垚鍗曚綅錛氭搗鍗楀ぇ瀛?涓浗姘翠駭縐戝鐮旂┒闄㈠崡嫻鋒按浜х爺絀舵墍,涓変簹甯?jìng)鎿v媧嬩笌娓斾笟鐩戞祴涓績(jī),涓撮珮?gòu)狗涓板吚L畺鍙戝睍鏈夐檺鍏徃,嫻峰崡闈掑埄姘翠駭綣佹畺鏈夐檺鍏徃,嫻峰崡嫻峰９姘翠駭楗叉枡鏈夐檺鍏徃
涓昏瀹屾垚浜哄憳錛氬懆姘哥伩,鏋楅粦鐫�,楠嗗墤,瀛欎簯,閽熼縛騫?鍛ㄤ紶鏈?榛勬搗,鏉ㄨ枃
鎴愭灉綆�浠嬶細(xì)
鍗靛艦椴抽補(bǔ)淇楃О閲戦渤錛屽叿鏈夌敓闀塊�熷害蹇�佸嚭鑲夌巼楂樸�佸吇孌栨晥鐩婂ソ絳変紭鐐癸紝鏄搗鍗楃瓑鎴戝浗鍗楁柟娌挎搗鍦板尯娣辨按緗戠鍏繪畺鐨勪富瑕侀奔綾伙紝娣卞彈娑堣垂鑰呭枩鐖便�傝嚜2008騫翠互鏉ワ紝鍦ㄧ鎶�閮ㄥ浗闄呭悎浣滈噸鐐歸」鐩�佸浗瀹惰嚜鐒剁瀛﹀熀閲戙�佹搗鍗楃渷閲嶅ぇ縐戞妧璁″垝欏圭洰銆佹搗鍗楃渷搴旂敤鎶�鏈爺鍙戜笓欏圭瓑璇鵑鐨勬敮鎸佷笅錛岀郴緇熷紑灞曚簡(jiǎn)鍗靛艦椴抽補(bǔ)鐨勮嫍縐嶈妯″寲綣佽偛銆佸繀闇�姘ㄥ熀閰稿拰楂樹(shù)笉楗卞拰鑴傝偑閰哥瓑钀ュ吇闇�姹傘�佹姉鐥呮満鍒躲�佷富瑕佺柧鐥呭強(qiáng)鍏跺畨鍏ㄩ珮鏁堟帶鍒舵妧鏈瓑鐮旂┒錛屽緩绔嬩簡(jiǎn)鍗靛艦椴抽補(bǔ)鍋ュ悍楂樻晥鍏繪畺鎶�鏈綋緋伙紝鎺ㄥ姩鍏舵垚涓哄綋鍓嶆搗鍗楀崟涓�鍏繪畺浜ч噺鏈�楂樼殑姘翠駭鍏繪畺鍝佺錛屼駭鐢熶簡(jiǎn)鏄捐憲鐨勭粡嫻庢晥鐩婂拰紺句細(xì)鏁堢泭銆備富瑕佹垚鏋滃涓嬶細(xì)
1. 鍗靛艦椴抽補(bǔ)鑻楃鏃╃箒鍙?qiáng)瑙勬ā鍖栫敓漶斿叧閿妧鏈爺絀朵笌搴旂敤錛氱郴緇熷紑灞曞嵉褰㈤渤椴硅嫍縐嶇箒鑲茬浉鍏蟲(chóng)妧鏈敾鍏籌紝緇樺埗浜?jiǎn)棣栧紶鍗靛舰椴抽矚w珮瀵嗗害閬椾紶榪為攣鍥捐氨錛屽緩绔嬩簡(jiǎn)鍏跺垎瀛愭爣璁拌緟鍔╄偛縐嶆妧鏈紱寤虹珛鍗靛艦椴抽補(bǔ)浜哄伐瀹剁郴鏋勫緩鎶�鏈�佷翰瀛愰壌瀹氭妧鏈拰褰㈡�佹�х姸蹇�熸祴綆楁妧鏈紝鑾峰緱浼樺娍鍗靛艦椴抽補(bǔ)瀹剁郴錛屼負(fù)鍏惰壇縐嶉�夎偛濂犲畾浜?jiǎn)閲嶈鍩杭媭錛涚巼鍏堢獊鐮翠簡(jiǎn)鍗靛艦椴抽補(bǔ)浜哄伐鏃╃箒鎶�鏈紝澶у箙鎻愰珮縐嶈嫍涓婂競(jìng)鏃墮棿錛屽垱閫犱簡(jiǎn)鏄捐憲鐨勭粡嫻庢晥鐩婂拰紺句細(xì)鏁堢泭銆?/p>
2. 鍗靛艦椴抽補(bǔ)钀ュ吇闇�姹傚強(qiáng)楂樻晥鐜繚楗叉枡鐮斿彂錛氱郴緇熺爺絀朵簡(jiǎn)鍗靛艦椴抽補(bǔ)瀵歸ゲ鏂欎腑蹇呴渶姘ㄥ熀閰搞�侀珮?shù)笉楗卞拰鑴傝偑閰搞�佺⒊姘村寲鍚堢墿鍜岀淮鐢熺礌鐨勯渶姹傞噺錛涚‘瀹氫簡(jiǎn)楗叉枡涓坊鍔犺灪鏃嬭椈鍜屾搗媧嬬孩閰墊瘝瀵規(guī)敼鍠勫吇孌栧嵉褰㈤渤椴逛綋鑹插獎(jiǎng)鍝嶏紝浠ュ強(qiáng)娣誨姞澶ц眴寮傞粍閰�佹灨鏉炲緋栥�佸綋褰掑緋栧拰榛勮姫澶氱硸瀵規(guī)彁楂樺嵉褰㈤渤椴規(guī)姉姘у寲鑳藉姏鍜屽厤鐤姏絳夌殑褰卞搷錛涘緩绔嬩簡(jiǎn)鍙戦叺璞嗙矔鍜屾販鍚堟鐗╄泲鐧芥簮鏈夋晥鏇夸唬楸肩矇鐨勬妧鏈柟娉曪紱鍒╃敤鐩稿叧鐮旂┒鎴愭灉綺懼噯閰嶆柟鍗靛艦椴抽補(bǔ)浜哄伐閰嶅悎楗叉枡錛屾樉钁楁彁楂樹(shù)簡(jiǎn)楗叉枡鐨勫埄鐢ㄧ巼鍗靛艦椴抽補(bǔ)鐨勭敓闀塊�熷害錛屾帹鍔ㄤ簡(jiǎn)鍗靛艦椴抽補(bǔ)浜哄伐鍏繪畺鐨勫仴搴峰彂灞曘�?/p>
3. 鍗靛艦椴抽補(bǔ)鎶楃梾鏈哄埗鐮旂┒錛氶�氳繃緇勫鎶�鏈強(qiáng)鐢熺墿淇℃伅瀛︾瓑鏂規(guī)硶錛岀郴緇熷垎鏋愪簡(jiǎn)鍗靛艦椴抽補(bǔ)鍩哄洜緇勫強(qiáng)鐤劇梾鍒烘縺妯″瀷錛岀瓫閫夊嚭涓庢姉鐥呭厤鐤浉鍏崇殑鍩哄洜300澶氫釜銆佽泲鐧?00澶氫釜錛屽茍鍒嗘瀽浜?jiǎn)鍏堕儴鍒嗗姛鑳藉Q屽～琛ヤ簡(jiǎn)鍗靛艦椴抽補(bǔ)鍏嶇柅鏈哄埗鐮旂┒鏂歸潰鐨勭┖鐧姐�傞嬈＄郴緇熷垎鏋愪簡(jiǎn)鍗靛艦椴抽補(bǔ)MHC鍩哄洜瀹舵棌鐨勫簭鍒楃粨鏋勭壒寰併�佸鎬佹�у拰鍏嶇柅鍔熻兘絳夛紝鍏嬮殕騫惰〃杈句簡(jiǎn)鍗靛艦椴抽補(bǔ)闃插盡绱犵瓑3縐嶆姉鑿岃偨浠ュ強(qiáng)騫叉壈绱犵瓑10縐嶉潪鐗瑰紓鎬у厤鐤洜瀛愶紝騫跺皢鍏朵綔涓哄厤鐤寮哄墏鍦ㄧ敓浜т笂搴旂敤錛涘埄鐢ㄨ泲鐧界粍鍜屼唬璋㈢粍瀛︽妧鏈彂鐜頒簡(jiǎn)涓庝腑鑽夎嵂闃叉不鍗靛艦椴抽補(bǔ)鐤劇梾鐩稿叧鐨勮泲鐧斤紝涓轟腑鑽夎嵂鍦ㄥ嵉褰㈤渤椴圭柧鐥呴槻娌諱腑鐨勫簲鐢ㄥ瀹氫簡(jiǎn)鍧氬疄鍩虹銆?/p>
4. 鍗靛艦椴抽補(bǔ)鐤劇梾鍙?qiáng)鍏跺畨鍏ㄩ珮鏁堟帶鍒舵妧鏈爺絀朵笌搴旂敤銆傜‘瀹氫簡(jiǎn)鍗靛艦椴抽補(bǔ)5縐嶉噸瑕佺柧鐥呭強(qiáng)鍏剁梾鍘燂紱鍒╃敤鎵�寤虹珛鐨勪腑鑽夎嵂蹇�熺瓫閫夊鉤鍙幫紝絳涢�夊茍鍒跺浜?jiǎn)闃叉舱d嵉褰㈤渤椴逛富瑕佺柧鐥呯殑3縐嶄腑鑽夎嵂緇勬柟錛屽湪鐢熶駭涓婂簲鐢ㄥ闃叉不鐩稿叧鐤劇梾鏁堟灉鏄捐憲錛涢�氳繃瀵瑰嵉褰㈤渤椴瑰搱緇存皬寮ц弻鐥呭師QT520鐨勫熀鍥犵粍嫻嬪簭鍙?qiáng)姣旇緝鍒嗘瀽锛尵p葷粺絳涢�夊嚭涓�鎵瑰厤鐤繚鎶ゅ師錛屽湪姝ゅ熀紜�涓婃瀯寤轟簡(jiǎn)閲嶇粍浜氬崟浣嶇柅鑻椼�佺粏鑿屼紶閫掍簹鍗曚綅鐤嫍銆丏NA鐤嫍鍙?qiáng)鍏嶇柅澧炲己鍓傚Q屽湪娣辨按緗戠鍏繪畺涓簲鐢ㄦ樉钁楁彁楂樹(shù)簡(jiǎn)鍗靛艦椴抽補(bǔ)鐨勫吇孌栨垚媧葷巼鍜屼駭鍝佽川閲忥紝淇濋殰浜?jiǎn)鎿v鍗楀嵉褰㈤渤椴瑰吇孌栫殑鍋ュ悍楂樻晥鍙戝睍銆?/p>
5. 鍗靛艦椴抽補(bǔ)鍋ュ悍楂樻晥鍏繪畺鎶�鏈綋緋繪瀯寤轟笌搴旂敤銆傛湰欏圭洰鎴愭灉宸插彂琛ㄨ鏂?8綃囷紙鍏朵腑SCI鏀跺綍璁烘枃33綃囷級(jí)錛屽嚭鐗堣憲浣?閮紝鑾鋒巿鏉冨浗瀹跺彂鏄庝笓鍒?浠訛紝鐢蟲(chóng)姤錛堝緟鎺堟潈錛夊浗瀹跺彂鏄庝笓鍒?浠躲�備富瑕佹垚鏋滃凡鍒嗗埆鍦ㄦ搗鍗楀嵉褰㈤渤椴硅嫍縐嶇敓浜с�侀ゲ鏂欏姞宸ュ拰娣辨按緗戠鍏繪畺鐨勯緳澶翠紒涓氬疄鐜頒駭涓氬寲搴旂敤錛屽茍杈愬皠鍏ㄧ渷涔冭嚦鎴戝浗鍗楁柟鍗靛艦椴抽補(bǔ)鍏繪畺鍖恒�傝繎5騫存潵錛屾湰鎴愭灉浜т笟鍖栧簲鐢ㄤ紒涓氭瘡騫寸箒鑲插嵉褰㈤渤椴逛紭鑹嫍縐?000~5000涓囧熬銆佺敓浜у嵉褰㈤渤椴歸ゲ鏂?.0~1.8涓囧惃銆佺敓浜у晢鍝侀奔0.6~1.2涓囧惃錛?騫村叡瀹炵幇浜у�奸�?6浜垮厓錛涘甫鍔?000浣欏悕鍐滐紙娓旓級(jí)姘戣劚璐嚧瀵岋紝鎺ㄥ姩鍗靛艦椴抽補(bǔ)鎴愪負(fù)褰撳墠嫻峰崡鍏繪畺浜ч噺鏈�楂樼殑姘翠駭鍝佺錛屼駭鐢熶簡(jiǎn)宸ㄥぇ鐨勭粡嫻庢晥鐩婂拰紺句細(xì)鏁堢泭銆?/p>
寰俊鎵竴鎵?br>鍒嗕韓鍒版湅鍙嬪湀
欏圭洰鍚嶇О錛氬嵉褰㈤渤椴硅妯″寲綣佽偛鍜屽仴搴烽珮鏁堝吇孌栨妧鏈爺絀朵笌浜т笟鍖栧簲鐢?/p>
鑾峰鍚嶇О鍙?qiáng)绛壘Uэ細(xì)2019騫村害嫻峰崡鐪佺瀛︽妧鏈浜岀瓑濂?/p>
涓昏瀹屾垚鍗曚綅錛氭搗鍗楀ぇ瀛?涓浗姘翠駭縐戝鐮旂┒闄㈠崡嫻鋒按浜х爺絀舵墍,涓変簹甯?jìng)鎿v媧嬩笌娓斾笟鐩戞祴涓績(jī),涓撮珮?gòu)狗涓板吚L畺鍙戝睍鏈夐檺鍏徃,嫻峰崡闈掑埄姘翠駭綣佹畺鏈夐檺鍏徃,嫻峰崡嫻峰９姘翠駭楗叉枡鏈夐檺鍏徃
涓昏瀹屾垚浜哄憳錛氬懆姘哥伩,鏋楅粦鐫�,楠嗗墤,瀛欎簯,閽熼縛騫?鍛ㄤ紶鏈?榛勬搗,鏉ㄨ枃
鎴愭灉綆�浠嬶細(xì)
鍗靛艦椴抽補(bǔ)淇楃О閲戦渤錛屽叿鏈夌敓闀塊�熷害蹇�佸嚭鑲夌巼楂樸�佸吇孌栨晥鐩婂ソ絳変紭鐐癸紝鏄搗鍗楃瓑鎴戝浗鍗楁柟娌挎搗鍦板尯娣辨按緗戠鍏繪畺鐨勪富瑕侀奔綾伙紝娣卞彈娑堣垂鑰呭枩鐖便�傝嚜2008騫翠互鏉ワ紝鍦ㄧ鎶�閮ㄥ浗闄呭悎浣滈噸鐐歸」鐩�佸浗瀹惰嚜鐒剁瀛﹀熀閲戙�佹搗鍗楃渷閲嶅ぇ縐戞妧璁″垝欏圭洰銆佹搗鍗楃渷搴旂敤鎶�鏈爺鍙戜笓欏圭瓑璇鵑鐨勬敮鎸佷笅錛岀郴緇熷紑灞曚簡(jiǎn)鍗靛艦椴抽補(bǔ)鐨勮嫍縐嶈妯″寲綣佽偛銆佸繀闇�姘ㄥ熀閰稿拰楂樹(shù)笉楗卞拰鑴傝偑閰哥瓑钀ュ吇闇�姹傘�佹姉鐥呮満鍒躲�佷富瑕佺柧鐥呭強(qiáng)鍏跺畨鍏ㄩ珮鏁堟帶鍒舵妧鏈瓑鐮旂┒錛屽緩绔嬩簡(jiǎn)鍗靛艦椴抽補(bǔ)鍋ュ悍楂樻晥鍏繪畺鎶�鏈綋緋伙紝鎺ㄥ姩鍏舵垚涓哄綋鍓嶆搗鍗楀崟涓�鍏繪畺浜ч噺鏈�楂樼殑姘翠駭鍏繪畺鍝佺錛屼駭鐢熶簡(jiǎn)鏄捐憲鐨勭粡嫻庢晥鐩婂拰紺句細(xì)鏁堢泭銆備富瑕佹垚鏋滃涓嬶細(xì)
1. 鍗靛艦椴抽補(bǔ)鑻楃鏃╃箒鍙?qiáng)瑙勬ā鍖栫敓漶斿叧閿妧鏈爺絀朵笌搴旂敤錛氱郴緇熷紑灞曞嵉褰㈤渤椴硅嫍縐嶇箒鑲茬浉鍏蟲(chóng)妧鏈敾鍏籌紝緇樺埗浜?jiǎn)棣栧紶鍗靛舰椴抽矚w珮瀵嗗害閬椾紶榪為攣鍥捐氨錛屽緩绔嬩簡(jiǎn)鍏跺垎瀛愭爣璁拌緟鍔╄偛縐嶆妧鏈紱寤虹珛鍗靛艦椴抽補(bǔ)浜哄伐瀹剁郴鏋勫緩鎶�鏈�佷翰瀛愰壌瀹氭妧鏈拰褰㈡�佹�х姸蹇�熸祴綆楁妧鏈紝鑾峰緱浼樺娍鍗靛艦椴抽補(bǔ)瀹剁郴錛屼負(fù)鍏惰壇縐嶉�夎偛濂犲畾浜?jiǎn)閲嶈鍩杭媭錛涚巼鍏堢獊鐮翠簡(jiǎn)鍗靛艦椴抽補(bǔ)浜哄伐鏃╃箒鎶�鏈紝澶у箙鎻愰珮縐嶈嫍涓婂競(jìng)鏃墮棿錛屽垱閫犱簡(jiǎn)鏄捐憲鐨勭粡嫻庢晥鐩婂拰紺句細(xì)鏁堢泭銆?/p>
2. 鍗靛艦椴抽補(bǔ)钀ュ吇闇�姹傚強(qiáng)楂樻晥鐜繚楗叉枡鐮斿彂錛氱郴緇熺爺絀朵簡(jiǎn)鍗靛艦椴抽補(bǔ)瀵歸ゲ鏂欎腑蹇呴渶姘ㄥ熀閰搞�侀珮?shù)笉楗卞拰鑴傝偑閰搞�佺⒊姘村寲鍚堢墿鍜岀淮鐢熺礌鐨勯渶姹傞噺錛涚‘瀹氫簡(jiǎn)楗叉枡涓坊鍔犺灪鏃嬭椈鍜屾搗媧嬬孩閰墊瘝瀵規(guī)敼鍠勫吇孌栧嵉褰㈤渤椴逛綋鑹插獎(jiǎng)鍝嶏紝浠ュ強(qiáng)娣誨姞澶ц眴寮傞粍閰�佹灨鏉炲緋栥�佸綋褰掑緋栧拰榛勮姫澶氱硸瀵規(guī)彁楂樺嵉褰㈤渤椴規(guī)姉姘у寲鑳藉姏鍜屽厤鐤姏絳夌殑褰卞搷錛涘緩绔嬩簡(jiǎn)鍙戦叺璞嗙矔鍜屾販鍚堟鐗╄泲鐧芥簮鏈夋晥鏇夸唬楸肩矇鐨勬妧鏈柟娉曪紱鍒╃敤鐩稿叧鐮旂┒鎴愭灉綺懼噯閰嶆柟鍗靛艦椴抽補(bǔ)浜哄伐閰嶅悎楗叉枡錛屾樉钁楁彁楂樹(shù)簡(jiǎn)楗叉枡鐨勫埄鐢ㄧ巼鍗靛艦椴抽補(bǔ)鐨勭敓闀塊�熷害錛屾帹鍔ㄤ簡(jiǎn)鍗靛艦椴抽補(bǔ)浜哄伐鍏繪畺鐨勫仴搴峰彂灞曘�?/p>
3. 鍗靛艦椴抽補(bǔ)鎶楃梾鏈哄埗鐮旂┒錛氶�氳繃緇勫鎶�鏈強(qiáng)鐢熺墿淇℃伅瀛︾瓑鏂規(guī)硶錛岀郴緇熷垎鏋愪簡(jiǎn)鍗靛艦椴抽補(bǔ)鍩哄洜緇勫強(qiáng)鐤劇梾鍒烘縺妯″瀷錛岀瓫閫夊嚭涓庢姉鐥呭厤鐤浉鍏崇殑鍩哄洜300澶氫釜銆佽泲鐧?00澶氫釜錛屽茍鍒嗘瀽浜?jiǎn)鍏堕儴鍒嗗姛鑳藉Q屽～琛ヤ簡(jiǎn)鍗靛艦椴抽補(bǔ)鍏嶇柅鏈哄埗鐮旂┒鏂歸潰鐨勭┖鐧姐�傞嬈＄郴緇熷垎鏋愪簡(jiǎn)鍗靛艦椴抽補(bǔ)MHC鍩哄洜瀹舵棌鐨勫簭鍒楃粨鏋勭壒寰併�佸鎬佹�у拰鍏嶇柅鍔熻兘絳夛紝鍏嬮殕騫惰〃杈句簡(jiǎn)鍗靛艦椴抽補(bǔ)闃插盡绱犵瓑3縐嶆姉鑿岃偨浠ュ強(qiáng)騫叉壈绱犵瓑10縐嶉潪鐗瑰紓鎬у厤鐤洜瀛愶紝騫跺皢鍏朵綔涓哄厤鐤寮哄墏鍦ㄧ敓浜т笂搴旂敤錛涘埄鐢ㄨ泲鐧界粍鍜屼唬璋㈢粍瀛︽妧鏈彂鐜頒簡(jiǎn)涓庝腑鑽夎嵂闃叉不鍗靛艦椴抽補(bǔ)鐤劇梾鐩稿叧鐨勮泲鐧斤紝涓轟腑鑽夎嵂鍦ㄥ嵉褰㈤渤椴圭柧鐥呴槻娌諱腑鐨勫簲鐢ㄥ瀹氫簡(jiǎn)鍧氬疄鍩虹銆?/p>
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