牡蠣諾卡氏菌病

病原: Nocardia crassostreae

貝類宿主：太平洋牡蠣Crassostrea gigas/歐洲牡蠣Ostrea edulis

主要癥狀：引起牡蠣局部或全身疾病，受感染組織器官表面常可見直徑約1cm的黃綠色膿皰突起，最后導致牡蠣大批死亡。組織病理觀察顯示病灶處革蘭氏染色陽性、PAS染色陽性、單個呈分枝形、顆粒狀嗜堿性的菌塊，病灶四周被緊密聚集的血淋巴細胞環繞。

檢測技術：引物PCR擴增，病灶組織膿皰壓片觀察

相關文獻：

Engelsma MY, Roozenburg I, Joly J P. First isolation of Nocardia crassostreae from Pacific oyster Crassostrea gigas inEurope. Dis Aquat Organ,2008, 80(3):229-34.

Noèlia Carrascoa, Ineke Roozenburga, Michal Voorbergen-Laarman,et al. Development of a real-time PCR for detection of the oyster pathogen Nocardia crassostreae based on its homogeneous 16S-23S rRNA intergenic spacer region. Journal of Invertebrate Pathology, Available online 19 July 2013.